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    Some Work, All Play

    Some Work, All Play

    About

    Five to ten topics, sometimes about running, with lots of love and enthusiasm and science. We dig deep into training, races, studies, pop culture, and much more! With Megan Roche, M.D. and David Roche!

    Hosted By

    David Roche and Megan Roche

    312. How Blood Volume Impacts Performance and Adapts Fast, The Scary Potential of Lactate Supplementation, The True GOAT, and The Circle Pit!

    312. How Blood Volume Impacts Performance and Adapts Fast, The Scary Potential of Lactate Supplementation, The True GOAT, and The Circle Pit!

    May 26, 2026
    1h 23m

    We basked in some amazing news before this great episode! The main topic was a breakdown of one of the most important elements of performance and health: blood volume. 

    Studies show that blood volume can seem to act as a synonym for fitness, with one finding that 6 weeks of training gains can be reversed with a phlebotomy that returns blood volume to baseline levels. Positive adaptations can happen in a few days, and it clearly matters for performance. If any other intervention worked like that, you’d assume everyone would be talking about it all the time. But blood volume is not discussed often! We pull back the curtain on the science.

    We also talked about a new review article on exogenous lactate supplementation. It might be a brave new world in the next 5 years, but right now there are more questions than answers. We speculate!

    And this one was full of cool topics! Other topics: the shockingly good news Megan has received in recent heart tests, our disdain for the Enhanced Games, recent age group doping news, the Satisfy Circle Pit, the true GOAT of endurance, running v. biking, uphill treadmill workouts, and lots more.

    Yes, David actually hit himself for a joke on this episode. Podcasts are definitely the medium for physical and visual comedy.

    We love you all! HUZZAH!

    -David and Megan

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    More from Some Work, All Play

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    309. The Marathon that Changed Running, Ultra GOAT to Western States, Misconceptions about Training Volume, A Supershoe Lawsuit, and A Hydration Study!

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    May 5, 2026